HyClone CDM4NS0 is an animal-derived component-free (ADCF), hydrolysate-free cell culture medium. This regulatory-friendly medium is developed to increase process yields of a variety of NS0 cell clones in the manufacture of monoclonal antibodies (MAbs). CDM4NS0 medium has been formulated to support the needs of NS0 cell clones and as such does not require cholesterol or glutamine synthetase (GS) supplementation. CDM4NS0 medium has been successfully tested in a variety of culture systems, including T-flasks, shaker flasks, and bioreactors using batch and fed-batch strategies. CDM4NS0 is available in liquid and powder formats in user-friendly packaging.
