HyClone CDM4MAb is a chemically defined and animal-derived component-free (ADCF) medium. This regulatory-friendly medium is designed to increase process yields for the manufacture of antibodies and antibody fragments for therapeutic use in a variety of engineered hybridoma and myeloma cell lines. CDM4MAb medium has been successfully tested in a variety of culture systems, including T-flasks, shaker flasks, and bioreactors including fed-batch and perfusion cultures. CDM4MAb medium does not contain phenol red and is available with or without L-glutamine and poloxamer 188. CDM4MAb is available in liquid and powder formats in user-friendly packaging.