CAT#:
55-804QB
Caprico Biotechnologies
CD4 PerCP-Cyanine5.5 Antibody Clone OKT4
Clone OKT4, Mouse IgG2b,k, 100 Tests/Unit
Product Overview
- CD4 is a 55kD type I transmembrane glycoprotein and a member of the immunoglobulin superfamily
- Highly specific and little to no cross reactivity to ensure accurate, reproducible results in Flow Cytometry
- >90% pure tested via polyacrylamide gel electrophoresis (PAGE)
- More conjugations and unit sizes available. Contact us at support@geneseesci.com to inquire.
- CD4 is also known as T4
Technical Specifications
| Conjugation | PerCP-Cy5.5 |
| Excitation Laser | Blue (488nm) |
| Reactivity | Human, Rhesus, Cynomolgus monkey |
| Host | Mouse |
| Antigen | CD4 |
| Clone | OKT4 |
| Isotype | IgG2b,k |
| Status | RUO |
| Size | 100 Tests/Unit |
| Storage | 2-8°C and protected from prolonged exposure to light |
| Formulation | PBS pH 7.2, 0.09% sodium azide |
| Immunogen | Human peripheral blood T lymphocytes |
| Clonality | Monoclonal |
Detailed Description
CD4 is a 55kD type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. It is a specific marker for T lymphocytes, monocytes, macrophages, and dendritic cells. Through interaction of MHC-II, CD4 facilitates cell-cell interaction, thymic differentiation, and activation of downstream signaling cascades. HIV infection of T-cells is instigated through binding of HIV to CD4. The OKT4 binds to the D3 domain of CD4 and does not inhibit HIV binding.
Each lot of these antibodies has been pre-titrated and tested by flow cytometric analysis of human PBMCs such that 0.5µg (unconjugated, Biotin) or 5µl (conjugated) of these products are sufficient for staining 1 million cells in a 100µl staining volume or 100µl of whole blood. It is recommended to titrate antibody reactivity empirically for optimal performance. Non-human primate cross-reactivity has been validated using Caprico’s PerCP-Cyanine5.5 conjugated OKT4 product. Do you need an antibody for an antigen you don't see on our website? Do you need a different conjugation than what we have listed? We have a wide selection of antigens with a variety of conjugations available. Please reach out to us at support@geneseesci.com.
Each lot of these antibodies has been pre-titrated and tested by flow cytometric analysis of human PBMCs such that 0.5µg (unconjugated, Biotin) or 5µl (conjugated) of these products are sufficient for staining 1 million cells in a 100µl staining volume or 100µl of whole blood. It is recommended to titrate antibody reactivity empirically for optimal performance. Non-human primate cross-reactivity has been validated using Caprico’s PerCP-Cyanine5.5 conjugated OKT4 product. Do you need an antibody for an antigen you don't see on our website? Do you need a different conjugation than what we have listed? We have a wide selection of antigens with a variety of conjugations available. Please reach out to us at support@geneseesci.com.
Citations
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