Cat #: 55-8031JB

Caprico Biotechnologies 1053145 CD3 mFluor™450 Antibody, Clone UCHT1, Mouse IgG1,k, 100 Tests/Unit

Cat #: 55-8031JB

Caprico Biotechnologies 1053145 CD3 mFluor™450 Antibody, Clone UCHT1, Mouse IgG1,k, 100 Tests/Unit


Clone UCHT1, Mouse IgG1,k

100 Tests/Unit

Brand: Caprico Biotechnologies

  • CD3, also known as T3, plays a role in antigen recognition, signal transduction, and T cell activation
  • Utilizes mFluor™ fluorescent labeling for greater light stability and brighter fluorescence
  • The monoclonal UCHT1 clone recognizes CD3? antigen
  • Highly specific and little to no cross reactivity to ensure accurate, reproducible results in Flow Cytometry
  • >90% pure tested via polyacrylamide gel electrophoresis (PAGE)
  • More conjugations and unit sizes available. Contact us at support@geneseesci.com to inquire.

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List Price: $428.90
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Clone UCHT1, Mouse IgG1,k

100 Tests/Unit

Brand: Caprico Biotechnologies

  • CD3, also known as T3, plays a role in antigen recognition, signal transduction, and T cell activation
  • Utilizes mFluor™ fluorescent labeling for greater light stability and brighter fluorescence
  • The monoclonal UCHT1 clone recognizes CD3? antigen
  • Highly specific and little to no cross reactivity to ensure accurate, reproducible results in Flow Cytometry
  • >90% pure tested via polyacrylamide gel electrophoresis (PAGE)
  • More conjugations and unit sizes available. Contact us at support@geneseesci.com to inquire.

The monoclonal UCHT1 clone recognizes CD3? antigen, a 20KDa transmembrane cell-surface protein that belongs to the immunoglobulin superfamily. The CD3 complex contains a CD3? chain, a CD3? chain, and two CD3? chains. These chains associate with a molecule known as the T-cell receptor (TCR) and the ?-chain (zeta-chain) to generate an activation signal in T lymphocytes. CD3? is expressed on T lymphocytes, NK-T cells, and to varying degrees on developing thymocytes. CD3 plays central roles in TCR signaling, T lymphocyte activation, and antigen recognition. Crosslinking of the TCR via plate bound UCHT1 monoclonal is widely used to study the activation T cell response in vitro.

mFluor™ fluorescent labeling dyes are developed specifically for flow cytometry applications to enable optimal multi-color detection. These dyes are excellent alternatives to the phycoprotein-based tandems that are quite difficult to couple to an antibody or other biomolecules and offer greater light stability and brighter fluorescence. The mFluor™ 450 fluorophore is a great alternative to these dyes: V450, Pacific Blue™, VioBlue®, eFluor® 450, Brilliant Violet 421 and Super Bright 436. Do you need an antibody for an antigen you don't see on our website? Do you need a different conjugation than what we have listed? We have a wide selection of antigens with a variety of conjugations available. Please reach out to us at support@geneseesci.com.

Conjugation mFluor™450
Excitation Laser Violet (405nm)
Reactivity Human
Host Mouse
Antigen CD3
Clone UCHT1
Isotype IgG1,k
Status RUO
Size 100 Tests/Unit
Storage 2-8°C and protected from prolonged exposure to light
Formulation PBS pH 7.2, 0.2% BSA (w/v), 0.09% sodium azide
Immunogen Thymocytes and peripheral blood lymphocytes from a Sézary Syndrome donor
Clonality Monoclonal

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